PFC Tablet: Each film coated tablet contains Pyridoxine Hydrochloride BP 25 mg, Folic Acid BP 2.5 mg & Cyanocobalamin BP 2 mg.
PFC is a medical food for the dietary management of hyperhomocysteinemia. Pyridoxine converts homocysteine to cysteine. Folic acid and cyanocobalamin together convert homocysteine to methionine. Thus PFC reduces homocysteine level in the blood.
PFC tablets are indicated for the distinct nutritional requirements of individuals under a physician's treatment for hyperhomocysteinemia; nutrient malabsorption or inadequate dietary intake; with particular emphasis for individuals with or at risk for atherosclerotic vascular disease in the coronary, peripheral, or cerebral vessels, or neurological disorders.
Dosage & Administration
Usual adult dose is one to two tablets daily or as directed by a physician.
Known hypersensitivity to any of the components in the product is a contraindication.
Warning & Precautions
Folic acid when administered as a single agent in doses above 0.1 mg daily may obscure pernicious anemia in that hematologic remission can occur while neurological manifestations remain progressive. Unmetabolized Folic Acid has the potential to reduce natural killer cells' cytotoxicity, which may result in an impaired immune response.
Allergic sensitization has been reported following both oral and parenteral administration of folic acid. Paresthesia, somnolence, nausea and headache have been reported with pyridoxine hydrochlloride. Mild transient diarrhea, polycythemia vera, itching, transitory exanthema, and the feeling of swelling of the entire body has been associated with cyanocobalamin.
Pyridoxine Hydrochloride should not be given to patients receiving the drug levodopa, because the action of levodopa is antagonized by Pyridoxine Hydrochloride. However; Pyridoxine Hydrochloride may be used concurrently in patients receiving a preparation containing both carbidopa and levodopa. Concurrent use of phenytoin and folic acid may result in decreased phenytoin effectiveness.
PFC Tablet: Each box contains 30's tablets in blister pack.