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T-Mycin

Tobramycin

Tobramycin is a member of aminoglycosides, which shows bactericidal activity by inhibiting normal protein synthesis of bacteria.

Product Details

Presentation

T-Mycin Sterile Eye Drops: Each ml contains Tobramycin USP 3 mg.
T-Mycin Sterile Eye Ointment: Each gram contains Tobramycin USP 3 mg.

Pharmacology

Tobramycin is a member of aminoglycosides, which shows bactericidal activity by inhibiting normal protein synthesis of bacteria.

Indication

For the treatment of external infections of the eye and its adnexa caused by susceptible bacteria. Appropriate monitoring of bacterial response to topical antibiotic therapy should accompany its use.

Dosage & Administration

Eye Drops: In mild to moderate disease, 1 drop into the affected eye(s) every 4 hours. In severe infections, 1 drop into the affected eye(s) hourly until improvement, following which dosage should be reduced prior to discontinuation.

Eye Ointment: In mild to moderate disease it should be applied thinly and evenly into the conjunctival sac of the affected eyes 2 to 3 times per day. For severe cases it should be applied thinly and evenly into the conjunctival sac of the affected eyes 3 to 4 times per day. Following improvement, treatment should be reduced prior to discontinuation.

Contraindications

Patients with known hypersensitivity to any of its components.

Warning & Precautions

As with other antibiotic preparations, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. If super-infection or drug resistance occurs, or irritation or sensitization to any of the components of this preparation develops, treatment should be discontinued and appropriate therapy should be initiated. The patient should be advised to consult a physician if improvement fails to occur, or if signs of super-infection occur.

Side effects

The most frequent side effects of Tobramycin are localized ocular toxicity and hypersensitivity, including lid itching and swelling and conjunctival erythema.

Use in special groups

Pregnancy: This drug should be used during pregnancy only if clearly needed.

Lactation: Because of the potential for adverse reactions in nursing infants from Tobramycin, a decision should be made whether to discontinue nursing the infant or discontinue the drug, taking into account the importance of the drug to the mother.

Packing

T-Mycin Sterile Eye Drops: Each plastic dropper bottle contains 5 ml eye drops.

T-Mycin Sterile Eye Ointment: Each tube contains 3 g eye ointment.

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