Our Products

Product details Products Home
AprocinAprocin

Aprocin

Ciprofloxacin

Ciprofloxacin is a synthetic 2nd generation fluoroquinolone having substantially enhanced antibacterial activity. It is a DNA gyrase inhibitor.

Product Details

Presentation

Aprocin-500 Tablet: Each film coated tablet contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 500 mg.
Aprocin Taste Masked Pellets for Suspension: After reconstitution each 5 ml suspension contains Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 250 mg.

Pharmacology

Ciprofloxacin is a synthetic 2nd generation fluoroquinolone having substantially enhanced antibacterial activity. It is a DNA gyrase inhibitor.

Indication

Ciprofloxacin is indicated for the following infections: Urinary tract infections, Acute sinusitis, Lower respiratory tract infections, Skin and skin structure infections, Infectious diarrhea, Typhoid fever (Enteric fever), Bone and joint infections, Acute uncomplicated cystitis in females, Chronic bacterial prostatitis, Uncomplicated cervical and urethral gonorrhea etc.

Dosage & Administration

Adults:

InfectionType of SeverityUnit DoseUsusal Duration
Urinary Tract InfectionAcute Uncomplicated100mg or 250 mg b.i.d3 days
Mild/Moderate250 mg bid7 to 14 days
Severe/Complicated500 mg b.i.d7 to 14 days
Acute SinusitisMild/Moderate500 mg b.i.d10 days
Lower respiratory tract infectionMild/Moderate500 mg b.i.d7 to 14 days
Severe/Complicated 750 mg b.i.d7 to 14 days
Skin and skin structure infectionMild/Moderate 500 mg b.i.d7 to 14 days
Severe/Complicated750 mg b.i.d7 to 14 days
Infectious diarrheaMild/Moderate/Severe500 mg b.i.d5 to 7 days
Typhoid feverMild/Moderate500 mg b.i.d10 days
Bone Joint infection Mild/Moderate500 mg b.i.d≥4 to 6 weeks
Severe/Complicated750 mg b.i.d ≥4 to 6 weeks
Chronic bacterial prostatitisMild/Moderate500 mg b.i.d28 days
Urethral & cervical Gonococcal infectionUncomplicated250mg single dose


Children:
Age over 1 year: Usually 5-15 mg/kg body weight twice daily. In acute pulmonary exacerbation of cystic fibrosis 20 mg/kg body weight twice daily.

Direction for preparation of Aprocin taste masked suspension :

Contraindications

Ciprofloxacin is contra-indicated in patients who have shown hypersensitivity to Ciprofloxacin or other quinolones.

Warning & Precautions

Ciprofloxacin should be used with caution in epileptics and patients with a history of CNS disorders. Crystalluria related to the use of Ciprofloxacin has been reported. Patients receiving Ciprofloxacin should be well hydrated and excessive alkalinity of the urine should be avoided.

Side effects

Ciprofloxacin is generally well tolerated. The most frequently reported side effects are nausea, diarrhea and rash.

Drug interaction

Increased plasma levels of theophylline have been observed following concurrent administration with Ciprofloxacin. Ciprofloxacin suspension should not be administered within 4 hours of medications containing magnesium, aluminium, calcium or iron salts as interference with absorption may occur.

Use in special groups

Use in pregnancy & lactation: Ciprofloxacin is not recommended during pregnancy & lactation.

Packing

Aprocin-500 Tablet: Each box contains 30's tablets in blister pack.
Aprocin Taste Masked Pellets for Suspension: Each box contains two bottles, large bottle containing Ciprofloxacin pellets and small bottle containing diluent for reconstitution of
60ml suspension.

Other Products from
Antibiotic
 
Erythromycin
Erythromycin
Cefixime
Ciprofloxacin
Amoxycillin Trihydrate
Chloramphenicol
Meropenem
Cefuroxime
Cefuroxime + Clavulanic Acid
Ceftriaxone
Azithromycin
Azithromycin
Besifloxacin Hydrochloride
Ceftazidime
Clindamycin
Cefradine
Cefepime
Rifaximin
Lomefloxacin
Lemefloxacin
Amikacin Sulfate
Sparfloxacin
Moxifloxacin
Moxifloxacin
Moxifloxacin (enriched with Xanthan Gum)
Gentamicin
Levofloxacin
Flucloxacillin
Tobramycin
Gatifloxacin
Cefpodoxime
Ofloxacin

© 2017. Aristopharma Ltd. All rights reserved.
Site by DIGITA iNTERACTIVE

HOME | PRODUCTS | FACILITIES | GLOBAL PRESENCE | NEWS | ABOUT US | CONTACT | CAREER

Webmail
Bookmark and Share