ARISTO D3 Oral & IM Injectable Solution: Each 1 ml ampoule contains Cholecalciferol BP (as Vitamin D3) 200000 IU.
Vitamin D3 is essential for normal bone growth and development and to maintain bone density. It is also necessary for utilization of both Calcium and Phosphorus. Vitamin D3 acts as a hormone and increases reabsorption of Calcium and Phosphorus by the kidney.
Vitamin D3 (Cholecalciferol) helps body to absorb calcium and phosphorus. It is used to treat and prevent bone disorders (such as rickets, osteomalacia). In combination with calcium it is used to treat or prevent bone loss (osteoporosis). It is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia). It may be used in kidney disease to keep calcium levels normal and allow normal bone growth.
Dosage & Administration
|Rickets||1 ampoule every 2 weeks for one month |
then 1 ampoule for every 4 months
|Osteoporosis||1 ampoule every 2 weeks for 3 months|
|Osteomalacia||1 ampoule every 2 weeks for 3 months|
|Tetany caused by hypocalcemia||1 ampoule for every 4 months which may be increased to 2 ampoules|
|Menopause||1 ampoule for every 6 months|
|Vitamin D deficiency||1 ampoule can be repeated 1 to 6 months later|
|Pregnacy||1/2 ampoule at 6th or 7th month|
|During Breast feeding||1/2 ampoule for every 6 months|
|Children up to 5 years||1 ampoule for every 6 months|
|Adolescent||1 ampoule for every 6 months|
|Elderly||1/2 ampoule for every 3 months|
- Injectable solution can be administered through IM or Oral route
- Prevention should be started early and continued to the 5th year of life
Cholecalciferol is contraindicated in all diseases associated with hypercalcaemia. It is also contraindicated in patients with known hypersensitivity to Cholecalciferol (or medicines of the same class) and any of the constituent excipients. Cholecalciferol is contraindicated if there is evidence of vitamin D toxicity.
Warning & Precautions
People with the following conditions should exercise with caution when considering taking vitamin D3 supplements:
- High blood calcium or phosphorus level
- Heart problems
- Kidney disease
Vitamin D3 must be taken with adequate amounts of both calcium and magnesium supplementation.
Generally all nutritional supplements are considered to be safe and well tolerable. However, few side-effects can generally occur including hypercalcaemia syndrome or calcium intoxication (depending on the severity and duration of hypercalcaemia), occasional acute symptoms include anorexia, headache, nausea, vomiting, abdominal pain or stomach ache and constipation with the administration of Cholecalciferol.
Use in special groups
Use in pregnancy: There is no evidence to suggest that vitamin D3 is teratogenic in humans even at very high doses. Cholecalciferol should be used during pregnancy only if the benefits outweigh the potential risk to the fetus.
Use in nursing mothers: It should be assumed that exogenous Cholecalciferol passes into the breast milk. In view of the potential for hypercalcaemia in the mother and for adverse reactions from
Cholecalciferol in nursing infants, mothers may breastfeed while taking Cholecalciferol, provided that the serum Calcium levels of the mother and infant are monitored.
ARISTO D3 Oral & IM Injectable Solution: Each box contains 1 ampoule of 1 ml Cholecalciferol BP (as Vitamin D3) solution.