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Neobion

Vitamin B1, B6 & B12

Neobion is a combination of Vitamin B1 (Thiamine), B6 (Pyridoxine) & B12 (Cyanocobalamin). These vitamins play essential role as co-enzyme for the metabolism of nervous system. Thus this combination normalizes the nerve cell metabolism. This combination supports the regeneration of nerve fibers and myelin sheath by activation of the metabolism and the natural repair mechanism. The combination of these 3 vitamins shows better efficacy than that of the individual components. In addition, Vitamin B1, B6 & B12 promote body's own repair mechanism and work in pain management.

Product Details

Presentation

Neobion Tablet: Each tablet contains Thiamine Nitrate (Vitamin B1) BP 100 mg, Pyridoxine Nitrate (Vitamin B6) BP 200 mg & Cyanocobalamin (Vitamin B12) BP 200 mcg.
Neobion Injection: Each 3 ml ampoule contains Thiamine Hydrochloride (Vitamin B1) BP 100 mg, Pyridoxine Hydrochloride (Vitamin B6) BP 100 mg & Cyanocobalamin (Vitamin B12) BP 1000 mcg.

Pharmacology

Neobion is a combination of Vitamin B1 (Thiamine), B6 (Pyridoxine) & B12 (Cyanocobalamin). These vitamins play essential role as co-enzyme for the metabolism of nervous system. Thus this combination normalizes the nerve cell metabolism. This combination supports the regeneration of nerve fibers and myelin sheath by activation of the metabolism and the natural repair mechanism. The combination of these 3 vitamins shows better efficacy than that of the individual components. In addition, Vitamin B1, B6 & B12 promote body's own repair mechanism and work in pain management.

Indication

Chronic pains like sciatica, lumbago, trigeminal neuralgia, facial paralysis, optic neuritis as well as neuropathy & cardiac complications. Besides these, deficiency exists of relevant vitamins.

Dosage & Administration

Neobion Tablet: 1-2 tablets three times daily.
Neobion Injection: In severe cases, 1 ampoule daily until the acute symptoms subsides. For milder cases, & follow up therapy 2 or 3 should be injected weekly.

Contraindications

It should not be used in patients on levodopa therapy.

Warning & Precautions

This combination (Vitamin B1+B6+B12) should be avoided in case of hypersensitivity to thiamine, cobalt or any other component of these ingredients. Cyanocobalamin should not be given before a diagnosis has been fully established because of the masking symptoms of subacute degeneration of the spinal cord.

Side effects

Very rarely hypersensitive reaction and sensitivity disturbance may occur.

Drug interaction

Pyridoxine (Vitamin B6) reduces therapeutic effect of levodopa but it does not occur if a dopa decarboxylase inhibitor is also given. Neomycin, chloramphenicol, aminosalisylic acid & histamine H2 receptor may reduce Vitamin B12 absorption.

Use in special groups

Use in pregnancy: Neobion is safe for pregnant woman.
Use in lactation: It is not known whether thiamine (Vitamin B1) is excreted in breast milk or not, but may be taken cautiously during lactation. Vitamin B6 & B12 have no adverse effect during lactation.
Use in children: Neobion may be given to children.

Packing

Neobion Tablet: Each box contains 60's tablets in blister pack.
Neobion Injection: Each box contains 10's ampoules.

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