Glucozid Tablet: Each Glucozid tablet contains Gliclazide BP 80 mg.
Gliclazide is a second-generation oral hypoglycemic sulfonylurea, which stimulates the release of insulin from pancreatic beta cells by facilitating Ca++ transport across the beta-cell membrane and decreases hepatic glucose output.
Glucozid (Gliclazide) is indicated for control of blood glucose in patients with non-insulin dependent diabetes mellitus (Type-II, maturity onset diabetes mellitus) whose hyperglycemia cannot be controlled by diet alone.
Dosage & Administration
Initially, 40-80 mg daily adjusted according to response, up to 160 mg as a single dose with breakfast; higher doses divided; Max. 320 mg daily.
Hypersensitivity to sulfonylurea, diabetes complicated by ketoacidosis with coma, as a sole therapy of insulin-dependent (Type-1) diabetes mellitus, diabetes when complicated by pregnancy & breast-feeding.
Warning & Precautions
Care should be exercised in patients with hepatic and/or renal impairment. In long term clinical trials patients with renal insufficiency have been treated satisfactory using Gliclazide at reduced doses.
Hypoglycemia may occur in concurrent conditions such as hepatic & renal diseases, alcohol intoxication and adrenal & pituitary insufficiency.
Gastro-intestinal disturbances such as vomiting, diarrhoea & cinstipation.
Allergic skin reactions including rash, pruritus, hermes replica bags and erythema, urticarias have been reported. These may be transient and may disappear despite continued use of the drug.
Androgens, anticoagulants, chloramphenicol, fluconazole, miconazole, histamine H2 antagonists, MAO inhibitors, phenylbutazone, probenecid, salicylates, sulfonamides, hermes replica handbags and tricyclic antidepressants may enhance the hypoglycemic effect of Glucozid.
Beta-blockers, rifampicin and thiazide diuretics, thyroid hormones, laxatives and oral contraceptives may decrease the hypoglycemic effect of Glucozid.
Use in special groups
In pregnancy & Lactation: Gliclazide should not be used.
Glucozid Tablet: Each box contains 50's tablets in blister pack.