Aristopharma Ltd. has launched Zavicef 2.5 g Injection, which is the preparation of Ceftazidime USP & Avibactam INN.

The ceftazidime component of Zavicef is a broad-spectrum cephalosporin antibiotic with in vitro activity against certain gram-negative and gram-positive bacteria. The bactericidal action of ceftazidime is mediated through binding to essential penicillin-binding proteins (PBPs). The avibactam component of Zavicef is a non-beta-lactam beta-lactamase inhibitor that inactivates certain beta-lactamases that degrade ceftazidime. Avibactam does not decrease the activity of ceftazidime against ceftazidime-susceptible organisms.