Indications

Prevention and treatment of Vitamin D3 deficiency & Vitamin D3 deficiency related diseases.

Dosage & Administration

Use of Tablet & Capsule:

Curative treatment:

Group of Patient	Dosages
Adult	40000 IU/week for 7 weeks and followed by 2000 IU/day as maintenance therapy if required.
Child	20000 IU in every 2 weeks for 6 weeks

Curative treatment:

Group of Patient	Dosages
Adult	20000 IU/month
Child	20000 IU in every 6 weeks

Use of Oral & IM Injectable Solution:

Curative treatment:

Disease	Dosages
Rickets	1 ampoule every 2 weeks for one month then 1 ampoule for every 4 months
Osteoporosis	1 ampoule every 2 weeks for 3 months
Osteomalacia	1 ampoule every 2 weeks for 3 months
Tetany caused by hypocalcemia	1 ampoule for every 4 months which may be increased to 2 ampoules
Menopause	1 ampoule for every 6 months
Vitamin D deficiency	1 ampoule can be repeated 1 to 6 months later


Preventive measures:

Period	Dosages
Pregnacy	1/2 ampoule at 6th or 7th month
During Breast feeding	1/2 ampoule for every 6 months
Children up to 5 years	1 ampoule for every 6 months
Adolescent	1 ampoule for every 6 months
Elderly	1/2 ampoule for every 3 months


- Injectable solution can be administered through IM or Oral route - Prevention should be started early and continued to the 5th year of life

 

Contrainidications

Cholecalciferol is contraindicated in all diseases associated with hypercalcaemia. It is also contraindicated in patients with known hypersensitivity to Cholecalciferol (or medicines of the same class) and any of the constituent excipients. Cholecalciferol is contraindicated if there is evidence of vitamin D toxicity.

Warning & Precautions

People with the following conditions should exercise with caution when considering taking vitamin D₃ supplements:
- High blood calcium or phosphorus level
- Heart problems
- Kidney disease

Vitamin D₃ must be taken with adequate amounts of both calcium and magnesium supplementation.

Side effects

Generally all nutritional supplements are considered to be safe and well tolerable. However, few side-effects can generally occur including hypercalcaemia syndrome or calcium intoxication (depending on the severity and duration of hypercalcaemia), occasional acute symptoms include anorexia, headache, nausea, vomiting, abdominal pain or stomach ache and constipation with the administration of Cholecalciferol.

Drug interaction

Use in special groups

Use in special groups: Use in pregnancy: There is no evidence to suggest that vitamin D3 is teratogenic in humans even at very high doses. Cholecalciferol should be used during pregnancy only if the benefits outweigh the potential risk to the fetus.

Use in nursing mothers: It should be assumed that exogenous Cholecalciferol passes into the breast milk. In view of the potential for hypercalcaemia in the mother and for adverse reactions from Cholecalciferol in nursing infants, mothers may breastfeed while taking Cholecalciferol, provided that the serum Calcium levels of the mother and infant are monitored.

Packing

ARISTO D3 2000 Tablet: Each box contains 30 tablets in alu-alu blister pack.

ARISTO D3 20000 Capsule: Each box contains 10 capsules in alu-alu blister pack.

ARISTO D3 40000 Capsule: Each box contains 7 capsules in alu-alu blister pack.

ARISTO D3 Oral & IM Injectable Solution: Each box contains 1 ampoule of 1 ml Cholecalciferol BP (as Vitamin D3) solution.