Faropenem is the 1st and only Oral “Penem Antibiotic” with broad-spectrum activity. It is bactericidal, with a strong affinity for the penicillin binding proteins (PBPs) of the cell wall, which is essential for the multiplication of bacteria; it, thus, acts by inhibiting the cell wall synthesis.
Faropenem is bactericidal, with a strong affinity for the penicillin binding proteins (PBPs) of the cell wall, which is essential for the multiplication of bacteria; it, thus, acts by inhibiting cell wall synthesis. Faropenem is highly stable against various beta lactamases. It is highly effective in different infections: Skin and skin structure infections, Lower & Upper respiratory tract infections, ENT infections & Urinary tract infections.
Novofar 150 Tablet: Each film coated tablet contains Faropenem Sodium Hydrate JP equivalent to Faropenem 150 mg.
Novofar 200 Tablet: Each film coated tablet contains Faropenem Sodium Hydrate JP equivalent to Faropenem 200 mg.
Novofar tablets are indicated in the treatment of the following infections:
Lower respiratory tract infections: Acute bronchitis, pneumonia, pulmonary suppuration.
Ear, nose, and throat (ENT) infections: Otitis externa, tympanitis, sinusitis.
Urinary tract infections: Pyelonephritis, cystitis, prostatitis, seminal gland inflammation.
Upper respiratory tract infections: Pharyngitis, tonsillitis.
Skin and skin structure infections: Pustular acne, folliculitis, contagious impetigo, erysipelas, lymphangitis, suppurative nail inflammation, subcutaneous abscess, hidradenitis (sweat gland inflammation), infective sebaceous cyst, chronic pyoderma, secondary infection of external wounds or surgical wounds.
| Indication | Dosage |
| Upper respiratory tract infections | 150 mg t.i.d., can be increased to 200 mg t.i.d. |
| ENT infections | 200 mg t.i.d., can be increased to 300 mg t.i.d. |
| Lower respiratory tract infections | 200 mg t.i.d., can be increased to 300 mg t.i.d. |
| Skin and skin structure infections | 150 mg t.i.d., can be increased to 200 mg t.i.d. |
| Urinary tract infections | 200 mg t.i.d., can be increased to 300 mg t.i.d. |
Faropenem is contraindicated in patients with known hypersensitivity to any of the components of this product or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactams.
Faropenem should be administered with caution in the following:
● Patients with a history of hypersensitivity to penicillin, cephem or carbapenem drugs.
● Patients with a family history of atopy.
● Patients with renal impairment. The dosage should be reduced or the interval between doses should be increased.
● Geriatric patients.
● Patients with poor oral intake or poor general state.
Common side effects of this drug are headache, nausea, vomiting, stomach pain and diarrhea.
Imipenem and Cilastatin sodium combination: It has been reported in studies that due to the obstruction of metabolic fermentation by cilastatin, the concentration of faropenem in the blood increases. Furosemide: It has been reported in studies that the kidney toxicity of faropenem increases. Sodium valproate: It has been reported in studies that due to joint usage with carbapenem drugs (meropenem, panipenem and imipenem-cilastatin sodium), the concentration of valproic acid in the blood reduces, and there is a recurrence of epileptic fits.
Pregnancy: Safety regarding therapy during pregnancy has not been established. In pregnant women or expectant mothers, the medicine should be given only if the benefits of the treatment are greater than the risks involved.
Nursing Mother: Faropenem is excreted in human milk. Therefore, faropenem should be given to nursing mothers only if the benefits outweigh the risks.
Pediatric Use: Safety regarding therapy in infants has not been established.
Geriatric Use: The half-life of Faropenem is prolonged in the elderly and this may be due to a decline in kidney functions, which results in high plasma concentrations. Therefore, in the elderly, start with a dose of 150 mg and monitor the patient for any undesirable effects.
If diarrhea and loose bowel movements appear, stop the medicine, monitor correctly, and take appropriate measures.
Novofar 150 Tablet: Each box contains 21 tablets in Alu-Alu Blister packs.
Novofar 200 Tablet: Each box contains 21 tablets in Alu-Alu Blister packs.
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