Carica papaya Leaf Extract has become popular as a herbal medicine for increasing the platelet count in dengue fever without any side effect and prevents the complication of thrombocytopenia.

Description

Carica papaya Leaf is a natural platelet booster.  The extract of papaya leaf has been shown to increase ALOX12 (arachidonate 12-lipoxygenase) gene activity by 15 times. Thus, Carica papaya leaf extract increases the platelet count in dengue fever without any side effect and prevents the complication of thrombocytopenia (low platelet count). It is also beneficial for people in treating digestive disorders due to the presence of an important enzyme papain.

Presentation

    Pepelif Syrup: Each 5 ml syrup contains Carica papaya Leaf Extract 275 mg.

Indications

    • Thrombocytopenia (low platelet count) associated with Dengue.
    • Thrombocytopenia (low platelet count) induced by chemotherapy.

Dosage & Administration

    For children more than 1 year and less than 5 years: 1 teaspoonful (5 mI) 3 times a day for 5 days.
    For more than 5 years and less than 18 years: 2 teaspoonful (10 mI) 3 times a day for 5 days.
    Above 18 years: 3 teaspoonful (15 mI) 3 times a day for 5 days or as directed by a physician.

Contrainidications

    Hypersensitivity, Pregnancy. In males with prostate dysfunction, such as BPH or prostate cancer, Carica papaya should be avoided as it increases the iron absorption. Excess iron may increase oxidative stress, especially in the aging male. Iron overload may increase the risk of developing prostate cancer.

Warning & Precautions

    Should be used with caution in individuals with bleeding disorders or those taking blood thinning medications such as aspirin or warfarin. Co administration of extracts of Carica papaya with oral hypoglycemic may lead to very low blood glucose as observed in one of the experimental animal study. Thus it is important to closely monitor the blood glucose levels regularly to avoid hypoglycemia.

Side effects

    No health hazards or side effects are known in conjunction with the proper administration of designated therapeutic dosages.

Drug interaction

    It has been found to increase the bioavailability of amiodarone and therefore the dose should be adjusted accordingly when co-administered with Carica papaya leaf extract. In vitro study demonstrated potentiating the action of various antibiotics like penicillin G, ampicillin, amoxyclav, cephalothin, polymyxin B, rifampicin, amikacin, nalidixic acid, gentamycin, chloramphenicol, ofloxacin when co-administered with Carica papaya. The extract of Carica papaya with antimicrobial agents possesses synergistic properties which act against pathogenic organisms.

Use in special groups

    Not recommended in pregnancy and lactation

Packing

    Pepelif Syrup: Each PET bottle contains 200 ml syrup.