Latanoprostene Bunod is a landmark breakthrough, a first-in-class monotherapy eye drop that simultaneously increases TRABECULAR AND UVEOSCLERAL OUTFLOW for effective Glaucoma management. It is Indicated for the treatment of Primary open-angle glaucoma or ocular hypertension. Apart from reducing IOP, it provides neuroprotection. Latanoprostene Bunod approved by USFDA on November, 2017.
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Latanoprostene Bunod (Zultan) represents a novel approach in glaucoma treatment due to its dual mechanism of action, targeting both the uveoscleral and trabecular meshwork outflow pathways to effectively lower intraocular pressure. It is a prescription-only medication designed for topical application to the eyes. The medication is metabolized into two relevant moieties upon administration: (1) Latanoprost acid, and (2) Butanediol mononitrate
Dosage & Administration: The recommended dosage is one drop in the affected eye(s) once daily in the evening. |
Zultan Ophthalmic Solution: Each ml contains Latanoprostene Bunod INN 0.24 mg
Zultan ophthalmic solution is indicated for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
The recommended dosage is one drop in the conjunctival sac of the affected eye(s) once daily in the evening.
Latanoprostene Bunod eye drops are contraindicated in patients who are hypersensitive to any component of this preparation.
The reported most common ocular adverse reaction is: Pigmentation, Eyelash Changes, Intraocular Inflammation, Macular Edema, Bacterial Keratitis etc.
Use in Pregnancy: There is no available human data for using Latanoprostene Bunod during pregnancy to inform of any drug-associated risks.
Lactation: There are no data on the presence of Latanoprostene Bunod in human milk, the effects on the breastfed infant, or the effects on milk production.
Use in the Paediatric population: Paediatric patients aged 16 years and younger are not recommended because of potential safety concerns related to increased pigmentation following long-term chronic use.
Use in Geriatric Patients: No overall clinical differences in safety or effectiveness have been observed between elderly and other adult patients.
Zultan Ophthalmic Solution: Each LDPE dropper bottle contains 3 ml of Sterile Eye Drops.
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