Aristodox Capsule: Each capsule contains Doxycycline Hyclate BP equivalent to Doxycycline 100 mg.
Aristodox is clinically effective in the treatment of a variety of infections caused by a wide range of Gram-negative and Gram-positive bacteria, as well as certain other microorganisms; such as-
Pneumonia: Aristodox is effective against single and multilobe pneumonia and broncho-pneumonia caused by susceptible strains of H. influenzae, Klebsiella pneumoniae, Pneumococci and other Streptococcus species, Staphylococcus and Mycoplasma pneumoniae.
Different respiratory tract infections: Bronchitis, tonsillitis, pharyngitis, otitis media and sinusitis, due to susceptible strains of pneumococci, H. influenzae, Staphylococcus species and Betahaemolytic streptococci.
Others: Genito-urinary tract infections, Gasto-intestinal infections, Ophthalmic infections, Soft tissue infections, Acne vulgaris and Acne conglobata.
Adults: The usual dose of oral Doxycycline is 2 capsules at a time on the first day of treatment or administered 1 capsule Doxycycline every 12 hours followed by a maintenance dose of 1 capsule/day.
In the management of more severe infections (particularly chronic infections of the urinary tract), 1 capsule every 12 hours is recommended.
For children above eight years of age: The recommended dosage schedule for children weighing 45 kg or less: 4.4 mg/kg on the first day followed by 2.2 mg/kg daily.
Acute gonococcal urethritis: 1 capsule twice daily for 2-4 days in male and until a cure has been obtained in female.
Chlamydial infections: 1 capsule twice daily for 7 days. Syphilis: 1 capsule twice daily for 14 days.
It is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines.
The use of Doxycycline during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of the teeth (yellow-gray-brown). Photosensitivity manifested by an exaggerated sunburn reaction has been observed in some individuals taking Doxycycline. Limit sun exposure.
Overgrowth of non-susceptible organisms, including fungi, may occur. Re¬evaluate therapy if superinfection occurs.
Anorexia, nausea, vomiting, diarrhea, skin rash, photosensitivity, urticaria and hemolytic anemia.
- Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage
- Avoid coadministration of tetracyclines with penicillin
- Absorption of Doxycycline is impaired by antacids containing aluminum, calcium or magnesium, bismuth subsalicylate and iron-containing preparations
- Barbiturates, carbamazepine and phenytoin decrease the half-life of Doxycycline.
Pregnancy: There are no adequate and well-controlled studies on the use of doxycycline in pregnant women. Should be avoided during pregnancy. Use in Lactation: Doxycycline is excreted in human milk. Use of Doxycycline during nursing should be avoided if possible.
Neonates and children: Doxycycline may cause permanent discoloration of the teeth (yellow-gray-brown) and so is contraindicated for neonates and children under 8 years.
Elderly: No special precautions are necessary in the elderly.
Aristodox Capsule: Each box contains 100 Capsules in blister pack.
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