Amoxycillin is a semi-synthetic antibiotic, an analog of ampicillin, with a broad spectrum of bactericidal activity against many gram-positive and gram-negative microorganisms. Amoxycillin is bactericidal against susceptible organisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell wall mucopeptides.
ARISTOMOX 250 Capsule: Each capsule contains Amoxycillin Trihydrate BP 287.50 mg equivalent to Amoxycillin 250 mg.
ARISTOMOX 500 Capsule: Each capsule contains Amoxycillin Trihydrate BP 575 mg equivalent to Amoxycillin 500 mg.
ARISTOMOX Powder for Suspension: After reconstitution each 5 ml contains Amoxycillin Trihydrate BP 143.50 mg equivalent to Amoxycillin 125 mg.
ARISTOMOX is indicated in the following bacterial infections:Respiratory tract Infections, otitis media, enteric fever, urinary tract infections, gram-negative septicemia, gonorrhea, other surgical infections, prevention of infective endocarditis.
Usual oral dose: 250 to 500 mg every 8 hours.
Children up to 10 years: 125 to 250 mg every 8 hours.
Under 20 kg body weights: 20 to 40 mg/kg/day in divided doses every 8 hours.
Infants less than 3 months: Maximum dose should be 30 mg/kg/day in divided doses every 12 hours.
Special Dosage:
Uncomplicated gonorrhea: A single dose of 3 g with probenecid 1 g.
Dental abscess: 3 g repeated after 8 hours.
Uncomplicated acute urinary tract infections: 3 g repeated after 10-12 hours.
Prophylaxis of endocarditis: 2 or 3 g 1 hour before dental procedures under local or no anesthesia.
Severe or recurrent respiratory tract infections: 3 g twice daily.
Otitis media: children 3-10 years, 750 mg twice daily for 2 days.
H. pylori eradication: In combination with metronidazole or clarithromycin and a bismuth compound or an antisecretory drug usual doses of Amoxycillin are 750 mg or 1g twice daily or 500 mg three times daily.
This drug is contraindicated in individuals with a history of an allergic reaction to any of the penicillins.
Superinfections may appear with the use of broad-spectrum antibiotics. Treatment should be discontinued if any superinfection appears with the use of ARISTOMOX and necessary treatment should be taken for the superinfection.
Nausea, vomiting, diarrhoea, rashes (discontinue treatment), rarely antibiotic associated colitis.
ARISTOMOX 250 Capsule: Box containing 120 capsules in blister pack.
ARISTOMOX 500 Capsule: Box containing 120 capsules in blister pack.
ARISTOMOX Powder for Suspension: Bottle containing dry powder for reconstitution of 100 ml oral suspension.
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