Emep MUPS highly effective in Gastroesophageal reflux disease (GERD) • Treatment of erosive reflux disease • Maintenance of healed esophagitis to prevent recurrence • Symptomatic treatment of gastroesophageal reflux • Eradication of Helicobacter pylori in combination with appropriate antibiotics • NSAID-associated gastric ulcers • Duodenal and gastric ulcer • Zollinger-Ellision syndrome.
• Emep MUPS is manufactured with buffered technology that ensures rapid acid neutralization & provides instant relief from hyperacidity
• Emep MUPS is manufactured with acid-resistant technology that ensures the protection of pellets from degradation in the stomach
• Emep MUPS contains a maximum number of pellets that ensures maximum absorption at the target site of action & optimum efficacy
• Emep MUPS is manufactured with DMF Grade Raw material which ensures maximum efficacy
Emep MUPS 20 Tablet: Each MUPS (Multiple-Unit Pellet System) tablet contains Esomeprazole Magnesium USP (as Trihydrate) equivalent to Esomeprazole 20 mg as enteric coated pellets.
Emep MUPS 40 Tablet: Each MUPS (Multiple-Unit Pellet System) tablet contains Esomeprazole Magnesium USP (as Trihydrate) equivalent to Esomeprazole 40 mg as enteric coated pellets.
• Gastroesophageal reflux disease (GERD): Treatment of erosive reflux - Maintenance of healed oesophagitis to prevent recurrence - Symptomatic treatment of gastroesophageal reflux
• Eradication of Helicobacter pylori in combination with appropriate antibiotics: - At the healing of Helicobacter pylori-associated duodenal ulcer - For the prevention of relapse of Helicobacter pylori-associated peptic ulcers
• Patients who have required continuous NSAID treatment: - At the healing of NSAID-associated gastric ulcers - For the prevention of NSAID-associated gastric and duodenal ulcers in patients at risk
• Duodenal and gastric ulcer
• Zollinger-Ellison syndrome
Adult from the age of 18:
|
Indication |
Dose |
Frequency |
|
Gastroesophageal reflux disease (GERD) |
||
|
Erosive Esophagitis |
40 mg |
Once daily for 4 weeks |
|
Maintenance therapy of healing of Erosive Esophagitis |
20 mg |
Once daily |
|
Stomach ulcer caused by NSAIDs |
20 mg |
Once daily for 4 to 8 weeks |
|
H. Pylori eradication (Esomeprazole MUPS tablet with Amoxicillin and Clarithromycin) |
20 mg |
Twice daily for 7 days |
|
Zollinger-Ellison syndrome |
40 mg to 80 mg |
Twice daily |
12 to 17 years old:
|
Indication |
Dose |
Frequency |
|
Gastroesophageal reflux disease (GERD) |
||
|
Erosive Esophagitis |
40 mg |
Once daily for 4 weeks |
|
Maintenance therapy of healing of Erosive Esophagitis |
20 mg |
Once daily |
|
H. Pylori eradication (Esomeprazole MUPS tablet with Amoxicillin and Clarithromycin) |
20 mg |
Twice daily for 7 days |
Esomeprazole MUPS Tablet is not recommended for children under 12 years of age.
|
Esomeprazole is contraindicated in patients with known hypersensitivity to any other components of the formulation.
Esomeprazole tablets should be used carefully if the patient has severe liver dysfunction and severe renal impairment.
More frequent: Headache, abdominal pain, diarrhoea, flatulence, nausea/ vomiting, and Less frequent: Dermatitis, pruritus, urticaria & dizziness.
Esomeprazole may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability such as Ketoconazole, Iron salts, and Digoxin.
Manufacturer advices caution and there is no information available. It is not known whether Esomeprazole is excreted in breast milk.
Emep MUPS 20 Tablet: Each box contains 60 tablets in Alu-Alu blister pack.
Emep MUPS 40 Tablet: Each box contains 30 tablets in Alu-Alu blister pack.
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