Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and antipyretic activities. Etoricoxib is a potent, orally active & highly selective cyclooxygenase-2 (COX-2) inhibitor. COX-2 is primarily responsible for the synthesis of prostanoid mediators of pain, inflammation and fever. Etoricoxib decreases these clinical signs and symptoms effectively with decreased GI toxicity. Moreover it has no effect on platelet function.
Etovan-60 Tablet: Each film coated tablet contains Etoricoxib INN 60 mg.
Etovan-90 Tablet: Each film coated tablet contains Etoricoxib INN 90 mg.
Etovan-120 Tablet: Each film coated tablet contains Etoricoxib INN 120 mg.
Etoricoxib is indicated for:
The recommended dose for adult and patient over 16 years:
Acute pain: 120 mg once daily. Etoricoxib 120 mg should be used only for acute symptomatic period, limited to a maximum of 8 days treatment. Chronic musculoskeletal pain: 60 mg once daily. Osteoarthritis: 30 mg once daily, increased if necessary to 60 mg once daily. Rheumatoid arthritis and ankylosing spondylitis: 90 mg once daily. Acute gout: 120 mg once daily for max. 8 days. Max. 60 mg daily in mild hepatic impairment; max. 60 mg on alternate days or 30 mg once daily in moderate hepatic impairment.
The recommended dose for adult and patient over 16 years:
Acute pain: 120 mg once daily. Etoricoxib 120 mg should be used only for acute symptomatic period, limited to a maximum of 8 days treatment. Chronic musculoskeletal pain: 60 mg once daily. Osteoarthritis: 30 mg once daily, increased if necessary to 60 mg once daily. Rheumatoid arthritis and ankylosing spondylitis: 90 mg once daily. Acute gout: 120 mg once daily for max. 8 days. Max. 60 mg daily in mild hepatic impairment; max. 60 mg on alternate days or 30 mg once daily in moderate hepatic impairment.
The drug should be avoided in case of severe hepatic impairment and in renal impairment (if creatinine clearance less than 30 ml/ minute)
Dry mouth, taste disturbance, mouth ulcer, flatulence, constipation, appetite and weight changes, chest pain , fatigue, paraesthesia, influenza like syndrome, myalgia etc. may occur.
Warfarin, Rifampicin, Methotrexate, ACE Inhibitor, Angiotensin II Antagonists, Lithium, Aspirin, Oral contraceptives may interact with Etoricoxib.
Use in pregnancy: Etoricoxib should be avoided in late pregnancy.
Use in nursing mother: Because of the possible adverse effects on nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug.
Etovan-60 Tablets: Each box contains 30's tablets in blister pack.
Etovan-90 Tablet: Each box contains 30's tablets in blister pack.
Etovan-120 Tablet: Each box contains 20's tablets in blister pack.
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