Description

Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) having properties of antipyretic and analgesic effects. A great number of pharmacological studies have proved that Indomethacin has strong anti-inflammatory, analgesic and antipyretic properties. Unlike the corticosteroids, the effect of Indomethacin is not related to the pituitary gland or the adrenals.

Presentation

    Reumacid Suppository: Each suppository contains Indomethacin USP 100 mg.

Indications

    Reumacid is indicated for the treatment of rheumatoid arthritis, ankylosing spondylitis, osteoarthritis (degenerative joint disease), gout, acute non-articular rheumatism (bursitis, synovitis, tendinitis).

Dosage & Administration

    100 mg at night and in the morning if required.

Contrainidications

    It is contraindicated in previously hypersensitive patient.

Warning & Precautions

    Caution to be taken in the patients with renal, cardiac, or hepatic impairment. Indometacin suppository should be used with caution in patients with psychiatric problems, epilepsy or parkinsonism since the drug may aggravate these conditions.

Side effects

    Headache, usually in the morning and mild vertigo may occur during the early weeks of therapy. These symptoms are transient and usually disappear with continued use or by reduction of the dose. Gastrointestinal reactions such as nausea, vomiting, diarrhea, epigastric and abdominal pain are often due to large doses of the drug and disappear when the dose is reduced.

Drug interaction

    It may interact with anticoagulants, lithium, diuretics, Beta-blockers, diflunisal, aspirin, probenecid and sulfonylureas.

Use in special groups

    Use in pregnancy: Not recommended for pregnant women, because at the present time clinical studies are insufficient.
    Use in children: Not recommended for children.

Packing

    Reumacid Suppository: Each box contains 20 suppositories in PVC / PE strip pack