Triamcinolone Acetonide (a derivative of Triamcinolone) in a compatible base. Topical steroids are primarily effective because of their anti-inflammatory, antipruritic & vasoconstrictive actions.

Description

Presentation

    Aristocort Cream: Each gram cream contains Triamcinolone Acetonide BP 1 mg.
    Aristocort Ointment: Each gram ointment contains Triamcinolone Acetonide BP 1 mg.

Indications

    Severe inflammatory skin disorders such as eczemas unresponsive to less potent corticosteroids; psoriasis & recalcitrant dermatoses such as chronic discoid lupus, erythematosus, lichen simplex chronicus, hypertrophic lichen planus & palmoplantar pustulosis.

Dosage & Administration

    Apply thinly to the affected areas 2-4 times daily or as directed by the physician.

Contrainidications

    Untreated bacterial, fungal, or viral skin lesions, rosacae (acne rosacae), perioral dermatitis; not recommended for acne vulgaris. Also contraindicated in infants under one (1) year.
    Moreover, Aristocort is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Warning & Precautions

    Triamcinolone acetonide should be avoided or given only under specialist supervision in psoriasis because although it may supress the psoriasis in short term, relapse or vigorous rebound occurs on withdrawl. Avoid prolonged use in infants and children. Avoid prolonged use on the face. Do not use in or around the eye. If irritation develops, the product should be discontinued and appropriate therapy instituted.

Side effects

    The following local adverse reactions have been reported with topical corticosteroids, especially under occlusive dressing: burning, itching, irritation, hypertrichosis, acneiform eruptions, hypopigmentation, allergic contact dermatitis, secondary infection, skin atrophy, striae, miliaria etc.

Drug interaction

Use in special groups

    Use in Pregnancy: The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effect from topically active corticosteroid. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
    Use in Lactation: Also caution should be exercised when topical corticosteroids are administered to a nursing mother.

Packing

    Aristocort Cream: Each tube contains 10 g cream.
    Aristocort Ointment: Each tube contains 10 g ointment.